The Use of Carnitine Rather than Renal Replacement Therapy for Sodium Valproate Poisoning
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چکیده
منابع مشابه
comparing replacement of metronidazole rather than prolongation of treatment duration in quadraple therapy for hp eradication
comparing replacement of metronidazole rather than prolongation of treatment duration in quadraple therapy for hp eradication
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A case of a severe overdose of sodium valproate (more than 10 times the therapeutic requirement) is discussed. The patient presented with central nervous, respiratory and cardiovascular depression and was treated with supportive therapy and haemoperfusion. However, on available data it would appear that haemoperfusion did not make a significant contribution towards the patient's recovery.
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A 48 year old patient deliberately poisoned herself with 25 g of sodium valproate and survived with supportive measures only. This case contradicts the experience of those who advocate aggressive management of such severe overdoses.
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ژورنال
عنوان ژورنال: Journal of the Intensive Care Society
سال: 2010
ISSN: 1751-1437
DOI: 10.1177/175114371001100112